表 4.

靶标蛋白TAB1与配体蛋白PML(5YUF)相互作用模式

Interaction mode between the target protein TAB1 and the ligand protein PML(5YUF)

Interaction pair of TAB1-PML	Distance (Å)	Category	Types
ASP458:OD2-ARG56:NH2	4.52	Electrostatic	Attractive Charge
GLU486:OE1-LYS68:NZ	5.34	Electrostatic	Attractive Charge
ASP494:OD1-THR75:OG1	2.57	Hydrogen Bond	Conventional Hydrogen Bond
TYR481-LYS65:NZ	4.65	Electrostatic	Pi-Cation
LEU461-LEU55	5.03	Hydrophobic	Alkyl
VAL482-PRO67	5.16	Hydrophobic	Alkyl
ALA485-LEU69	5.47	Hydrophobic	Alkyl
ARG489-LEU69	4.07	Hydrophobic	Alkyl
LEU490-PRO67	5.08	Hydrophobic	Alkyl
TYR481-CYS66	5.40	Hydrophobic	Pi-Alkyl
PRO389-PHE52	4.97	Hydrophobic	Pi-Alkyl
LEU461-PHE54	4.79	Hydrophobic	Pi-Alkyl
VAL493-HIS74	4.97	Hydrophobic	Pi-Alkyl