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敲低NPHP1表达对TNF-α信号通路的影响
Effect of NPHP1 knockdown on TNF-α signaling pathway in HK2 cells. A-H: Relative mRNA levels normalized to GAPDH. Compared with NPHP1WT HK2 cells, the expression of TNF-α, C/EBPβ, CXCL5, IL-1β and IL-6 was up-regulated, and the expression of CCL2 and CCL20 was down-regulated in NPHP1KD HK2 cells (n=3). *P < 0.05; **P < 0.01.
