表 1.
广义估计方程分析不同时间点与细胞因子、性激素和代谢指标的关系
Generalized estimation equation for analyzing association of cytokines, hormonal and metabolic with different time points
| Parameters | 3 months later | 6 months later | |||
| OR (95% CI) | P | OR (95% CI) | P | ||
| OR: Odds ratio; CI: Confidence interval; se: Serum; sa: Saliva; BMI: Body mass index; WHR: Waist hip rate; TG: Triglyceride; TC: Cholesterol; HDL: High density lipoprotein; FPG: Fasting plasma glucose; FI: Fasting insulin; FSH: Follicle-stimulating hormone; LH: Luteinizing hormone; T: Testosterone; P: Progesterone; E2: Estradiol; IL-6: Interleukin-6; IL-17A: Interleukin-17A; MMP-8: Matrix metalloproteinases-8; TNF-α: tTumor necrosis factor-α; PD: Probe depth; FMPS: Dental plaque score; BOP: Gingival bleeding index of probe; CAL: Clinical attachment level. | |||||
| TG | 1.271 (1.002, 1.812) | 0.048 | 1.170 (0.942, 1.453) | 0.155 | |
| TC | 1.040 (0.858, 1.262) | 0.688 | 0.946 (0.763, 1.172) | 0.610 | |
| HDL | 1.165 (1.060, 1.280) | 0.001 | 1.115 (1.015, 1.224) | 0.023 | |
| FI | 4.898 (0.011, 213.06) | 0.608 | 3.092 (0.000, 843.23) | 0.212 | |
| FPG | 1.042 (0.938, 1.159) | 0.442 | 1.145 (1.027, 1.276) | 0.015 | |
| FSH, | 0.661 (0.140, 3.109) | 0.600 | 0.152 (0.055, 0.426) | ＜0.001 | |
| LH | 1.222 (1.028, 1.765) | 0.015 | 1.448 (1.050, 4.040) | 0.047 | |
| LH/FSH | 1.082 (1.008, 1.139) | 0.041 | 1.121 (1.011, 1.682) | 0.033 | |
| T | 0.884 (0.815, 0.960) | 0.003 | 0.950 (0.877, 1.030) | 0.213 | |
| P | 1.034 (0.370, 2.888) | 0.949 | 0.715 (0.331, 1.543) | 0.393 | |
| E2 | 1.055 (＜0.001, 7.774) | 0.995 | 0.043 (＜0.001, 3.023) | 0.081 | |
| se IL-6 | 0.785 (0.488, 1.264) | 0.319 | 1.597 (1.088, 2.878) | 0.011 | |
| se IL-17A | 70.201 (0.002, 219.796) | 0.742 | 13.375 (＜0.001, 47.907) | 0.516 | |
| se MMP-8 | 1.735 (0.512, 5.881) | 0.376 | 0.820 (0.216, 3.112) | 0.771 | |
| se TNF-α | 3.923 (0.415, 37.481) | 0.876 | 7.088 (0.031, 16.453) | 0.898 | |
| sa IL-6 | 5.530 (0.970, 31.528) | 0.054 | 28.305 (2.471, 324.207) | 0.007 | |
| sa IL-17A | 6.796 (0.349, 13.234) | 0.386 | 8.219 (0.037, 18.075) | 0.423 | |
| sa MMP-8 | 1.098 (1.024, 5.028) | 0.043 | 23.424 (5.407, 101.522) | 0.007 | |
| sa TNF-α | 1.097 (0.051, 2.378) | 0.138 | 6.838 (0.025, 18.662) | 0.212 | |
| FMPS | 0.095 (＜0.001, 45.104) | 0.454 | 1.987 (0.010, 395.563) | 0.799 | |
| BOP | 1.018 (0.990, 1.046) | 0.214 | 1.096 (1.035, 1.989) | 0.007 | |
| PD | 1.078 (1.022, 1.137) | 0.045 | 1.094 (1.045, 1.967) | 0.003 | |
| PD≥4 mm (%) | 1.366 (1.158, 1.843) | 0.018 | 1.426 (1.211, 1.861) | 0.017 | |
| PD≥6 mm (%) | 0.942 (0.807, 1.100) | 0.450 | 1.075 (0.974, 1.187) | 0.153 | |
| CAL=1-2 mm (%) | 1.379 (1.164, 1.877) | 0.023 | 1.432 (1.212, 1.878) | 0.020 | |
| CAL=3-4 mm (%) | 0.942 (0.807, 1.100) | 0.450 | 1.075 (0.974, 1.187) | 0.153 | |