表 2.
代谢指标、性激素、细胞因子和牙周指标之间的Spearman相关性分析
Spearman correlation analysis between metabolic indicators, sex hormones, cytokines and periodontal indicators
| Factor | se IL-6 | se IL-17A | se MMP8 | se TNF-α | sa IL-6 | sa IL-17A | sa MMP8 | sa TNF-α | FMPS | BOP | PD |
| Se: Serum; sa: Saliva; TG: Triglyceride; HDL: High density lipoprotein; FPG: Fasting plasma glucose; FI: Fasting insulin; FSH: Follicle-stimulating hormone; LH: Luteinizing hormone; T: Testosterone; P: Progesterone; E2: Estradiol; IL-6: Interleukin-6; IL-17A: Interleukin-17A; MMP-8: Matrix Metalloproteinases-8; TNF-α: Tumor necrosis factor-α; PD: Probe depth; FMPS: Dental plaque score; BOP: Gingival bleeding index of probe; CAL: Clinical attachment level. *P<0.05; **P<0.01. | |||||||||||
| T | -0.089 | -0.135 | 0.177* | -0.134 | 0.017 | 0.177* | 0.070 | -0.029 | -0.161* | -0.101 | -0.096 |
| TG | -0.104 | -0.135 | 0.315** | 0.006 | -0.193* | -0.242** | -0.041 | -0.209* | 0.027 | 0.032 | 0.020 |
| TC | -0.218** | -0.025 | 0.306** | -0.045 | -0.147 | -0.322** | -0.016 | -0.245** | -0.002 | 0.041 | 0.121 |
| HDL | -0.036 | -0.042 | -0.015 | -0.092 | -0.051 | -0.092 | 0.059 | -0.044 | -0.044 | -0.087 | 0.029 |
| FPG | 0.119 | 0.009 | 0.158 | -0.034 | 0.054 | 0.113 | 0.066 | 0.097 | -0.157 | -0.060 | -0.147 |
| FI | -0.088 | -0.140 | 0.164* | -0.024 | -0.028 | -0.085 | -0.159 | -0.062 | -0.073 | 0.024 | -0.028 |
| LH | -0.141 | 0.139 | 0.206* | 0.060 | -0.033 | 0.004 | 0.043 | 0.051 | 0.051 | 0.105 | 0.248** |
| FSH | 0.081 | 0.045 | -0.139 | 0.014 | -0.142 | -0.048 | -0.023 | 0.023 | -0.115 | -0.023 | -0.055 |
| LH/FSH | -0.217** | 0.157 | 0.309** | 0.066 | 0.069 | 0.074 | 0.057 | 0.059 | 0.088 | 0.123 | 0.267** |
| E2 | -0.248** | 0.143 | 0.165* | 0.038 | -0.073 | 0.013 | -0.013 | -0.164* | -0.031 | 0.033 | 0.154 |
| P | -0.156 | 0.046 | 0.239** | 0.026 | -0.050 | -0.055 | 0.001 | -0.081 | 0.125 | -0.016 | -0.023 |
| FMPS | 0.089 | 0.069 | 0.002 | -0.009 | -0.002 | -0.119 | 0.254** | -0.058 | 1.000 | 1.000 | 0.373** |
| BOP | 0.179* | -0.066 | 0.064 | -0.115 | -0.019 | -0.058 | 0.412** | -0.063 | 0.574** | 0.747** | 0.747** |
| PD | 0.036 | -0.034 | 0.138 | -0.080 | 0.005 | -0.116 | 0.310** | -0.115 | 0.373** | 0.604** | 1.000 |
| PD≥4 mm | 0.130 | 0.068 | 0.081 | -0.067 | -0.064 | -0.100 | 0.390** | -0.015 | 0.302** | 0.619** | 0.705** |
| CAL1-2 mm | 0.129 | 0.055 | 0.077 | -0.076 | -0.048 | -0.099 | 0.378** | -0.028 | 0.314** | 0.619** | 0.722** |