Genome organization of CaMV ORFs I-VII, functional maps of MP, ATF, and VAP. CP, capsid precursor polyprotein; POL, polymerase polyprotein (reverse transcriptase/RNase H and aspartic protease); TAV, transactivator/viroplasmin. MP, VAP, and ATF are depicted by boxes with amino acid numbers indicated. Hatched boxes in MP and VAP represent the nucleic acid-binding domains, and the black boxes represent the coiled coils. tfd, tubule-forming domain; ffd, focus-forming domain; vbd, virus-binding domain.