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. 2024 Feb 7;15:1325186. doi: 10.3389/fphar.2024.1325186

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Copyright © 2024 Perelló, Alberti, Torres, Ferrer, Perez, Bassissi, Gold, Raggi, Chertow and Salcedo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Final PK/PD Model for the Relation Between Average Hexasodium Fytate Maximum Concentration (C_max) and Average Inhibition of Hydroxyapatite Crystallization (% PD inhibition). Black points and lines: mean (±SE) for % PD inhibition by C_max quartile. Box plots for C_max: diamond represents the arithmetic mean, vertical line represents the median, central rectangle spans the first quartile to the third quartile (the interquartile range), and whiskers show the locations of the minimum and maximum.