Table 1. Embryos from Fe and C-exposed males.
Dose, Gy | No. (experiment) | Stage exposed* | Fraction fertilized† | Embryos developed | Effective loci, 104 | DL | TM | VM | DL frequency‡ | TM frequency,§ 10−4 |
---|---|---|---|---|---|---|---|---|---|---|
56-GeV Fe-exposed males | ||||||||||
Historical controls | 27,870 | 12.2 | 700 | 4 | 1 | 0.025 | 0.33 | |||
0.3 | 48 (1) | Sperm | 0.84 | 1,698 | 0.84 | 110 | 7 | 1 | 0.065 | 8.3 |
Tids | 0.87 | 4,024 | 2.00 | 191 | 12 | 0 | 0.048 | 6.0 | ||
Gonia | 0.86 | 11,288 | 5.89 | 520 | 11 | 1 | 0.046 | 1.9 | ||
1.0 | 36 (1) | Sperm | 0.86 | 1,353 | 0.67 | 143 | 19 | 1 | 0.106 | 28 |
Tids | 0.82 | 2,925 | 1.45 | 276 | 43 | 0 | 0.094 | 30 | ||
Gonia | 0.83 | 8,411 | 4.32 | 382 | 13 | 1 | 0.045 | 3.0 | ||
1.0 | 38 (2) | Sperm | 0.69 | 1,200 | 0.60 | 132 | 16 | 0 | 0.110 | 27 |
Tids | 0.73 | 3,436 | 1.71 | 291 | 45 | 2 | 0.085 | 26 | ||
Gonia | 0.47 | 8,359 | 4.16 | 318 | 2 | 1 | 0.038 | 0.48 | ||
2.0 | 40 (2) | Sperm | 0.67 | 1,466 | 0.72 | 284 | 43 | 0 | 0.194 | 59 |
Tids | 0.69 | 3,122 | 1.54 | 548 | 78 | 5 | 0.176 | 51 | ||
Gonia | 0.33 | 7,368 | 3.64 | 287 | 2 | 1 | 0.039 | 0.55 | ||
3.5-GeV C-exposed males | ||||||||||
Historical controls | 37,968 | 18.6 | 1,027 | 6 | 1 | 0.027 | 0.32 | |||
2.0 | 76 | Sperm | — | 927 | .452 | 195 | 20 | 2 | 0.210 | 44 |
Tids | — | 2,093 | 1.03 | 268 | 26 | 2 | 0.128 | 25 | ||
Gonia | — | 5,735 | 2.99 | 327 | 6 | 1 | 0.057 | 2.0 | ||
4.75 | 80 | Sperm | — | 1,759 | 0.77 | 696 | 83 | 5 | 0.396 | 107 |
Tids | — | 3,629 | 1.58 | 1,064 | 127 | 9 | 0.293 | 80 | ||
Gonia | — | 3,189 | 1.60 | 460 | 53 | 3 | 0.144 | 33 | ||
8.07 | 40 | Sperm | — | 1,041 | 5.04 | 630 | 121 | 0 | 0.605 | 240 |
Tids | — | 2,055 | 10.0 | 940 | 176 | 5 | 0.457 | 176 |
Matings of exposed sperm, days 1-3; spermatids (tids), days 4-9; spermatogonia (gonia), days 32-149 for experiment 1 and days 46-117 for experiment 2. Only one experiment was performed for 3.5-GeV C-exposed males.
The no. of fertilized embryos divided by the no. of embryos laid. (Fraction fertilized not included for 3.5 GeV C-exposed males because data were only partially collected.)
DL frequency per developed embryo.
TM per effective locus.