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. 2024 Feb 7;15:1303342. doi: 10.3389/fphar.2024.1303342

TABLE 1.

Hexarelin decreased cytokine levels in lung homogenates at day 3 after SARS-CoV-2 infection.

Cytokines Group (n = 3) pg/mg ± SEM p values
CCL2 0.9% NaCl 131 ± 5 0.0082*
Hexarelin 73 ± 11
CCL3 0.9% NaCl 6.9 ± 0.5 0.1066
Hexarelin 5.0 ± 0.8
CCL4 0.9% NaCl 12.1 ± 1.4 0.0084*
Hexarelin 5.0 ± 0.5
CXCL9 0.9% NaCl 431 ± 84 0.7000
Hexarelin 383 ± 12
GROα 0.9% NaCl 7.5 ± 0.8 0.0978
Hexarelin 5.3 ± 0.7
IFNα 0.9% NaCl 23 ± 1 0.0463*
Hexarelin 13 ± 3
IFNβ 0.9% NaCl 13 ± 2 0.2978
Hexarelin 9 ± 2
IFNγ 0.9% NaCl 1.7 ± 0.2 0.0477*
Hexarelin 1.1 ± 0.1
IL-1β 0.9% NaCl 1.5 ± 0.1 0.0698
Hexarelin 1.2 ± 0.1
IL-6 0.9% NaCl 32 ± 4 0.1632
Hexarelin 24 ± 3
IP-10 0.9% NaCl 96 ± 9 0.7891
Hexarelin 91 ± 14
RANTES 0.9% NaCl 167 ± 11 0.1413
Hexarelin 144 ± 7
TNFα 0.9% NaCl 7.5 ± 0.8 0.0978
Hexarelin 5.3 ± 0.7