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. 2024 Feb 7;12:1289918. doi: 10.3389/fpubh.2024.1289918

Table 1.

Sociodemographic, knowledge, worries and attitudes toward MPX and MPX vaccine among MSM in China (n = 1,093).

Variables Total (N = 1,093) Unwilling (n = 94) Willing (n = 999) P-value
Sociodemographic
Age, year 0.049
<26 518 (47.4) 41 (43.6) 477 (47.8)
26–40 494 (45.2) 51 (54.3) 443 (44.3)
>40 81 (7.4) 2 (2.1) 79 (7.9)
Current residence area 0.439
Rural 93 (8.5) 10 (10.6) 83 (8.3)
Urban 1,000 (91.5) 84 (89.4) 916 (91.7)
HIV status 0.669
Negative 709 (64.9) 59 (62.8) 650 (65.1)
Positive 196 (17.9) 20 (21.3) 176 (17.6)
Unknown 188 (17.2) 15 (16) 173 (17.3)
Marital status/social relationship status 0.001
Single (unmarried, divorced or widowed) 855 (78.2) 61 (64.9) 794 (79.5)
Married 184 (16.8) 22 (23.4) 162 (16.2)
Cohabitation 54 (5) 11 (11.7) 43 (4.3)
Education 0.954
High school or below 181 (16.6) 15 (16) 166 (16.6)
Junior or higher vocational college 260 (23.8) 24 (25.5) 236 (23.6)
Undergraduate 557 (51) 46 (48.9) 511 (51.2)
Postgraduate 95 (8.6) 9 (9.6) 86 (8.6)
Occupation 0.486
Farmer or worker 120 (11) 14 (14.9) 106 (10.6)
Student 227 (20.8) 14 (14.9) 213 (21.3)
Company or government employee 455 (41.6) 39 (41.5) 416 (41.6)
Business or self-employed 213 (19.5) 19 (20.2) 194 (19.4)
Unemployed 78 (7.1) 8 (8.5) 70 (7)
Monthly income 0.159
No fixed 211 (19.3) 18 (19.2) 193 (19.4)
<2,000 98 (9) 8 (8.5) 90 (9)
2,000-4,999 372 (34) 24 (25.5) 348 (34.8)
5,000-9,999 297 (27.2) 28 (29.8) 269 (26.9)
>10,000 115 (10.5) 16 (17) 99 (9.9)
Sexual orientation 0.246
Heterosexual 402 (36.8) 37 (39.4) 365 (36.6)
Homosexual 495 (45.2) 35 (37.2) 460 (46)
Bisexual 155 (14.2) 16 (17) 139 (13.9)
Pansexual and other 41 (3.8) 6 (6.4) 35 (3.5)
History of chronic diseases 0.217
No 236 (21.6) 25 (26.6) 211 (21.1)
Yes 857 (78.4) 69 (73.4) 788 (78.9)
History of STDs 0.200
No 859 (78.6) 69 (73.4) 790 (79.1)
Yes 234 (21.4) 25 (26.6) 209 (20.9)
Knowledge of MPX and monkeypox vaccine
Awareness of MPX 0.006
No 329 (30.1) 40 (42.6) 289 (28.9)
Yes 764 (69.9) 54 (57.4) 710 (71.1)
Frequency of following MPX information 0.953
Less than one times in a week 272 (35.6) 4 (7.4) 45 (6.4)
One or more times in a week 443 (58) 19 (35.2) 253 (35.6)
Not focused 49 (6.4) 31 (57.4) 412 (58)
Having good knowledge of MPX 0.017
No 432 (39.5) 48 (51.1) 384 (38.4)
Yes 661 (60.5) 46 (48.9) 615 (61.6)
Being considered people could be re-infected MPXV 0.017
Disagree 76 (7) 12 (12.8) 64 (6.4)
Unsure 347 (31.7) 35 (37.2) 312 (31.2)
Agree 670 (61.3) 47 (50) 623 (62.4)
Being considered MSM are high-risk population of MPXV infection 0.049
Disagree 91 (8.3) 11 (11.7) 80 (8)
Uncertain 273 (25) 31 (33) 242 (24.2)
Agree 729 (66.7) 52 (55.3) 677 (67.8)
Having ever heard of smallpox (cowpox) vaccine <0.001
No 139 (12.7) 27 (28.7) 112 (11.2)
Yes 954 (87.3) 67 (71.3) 887 (88.8)
Knowing a(Smallpox vaccine, ACAM2000) and b(JYNNEOS) are currently used to prevent MPX * 0.020
I do not know 460 (42.1) 52 (55.3) 408 (40.9)
Having ever heard of a and b* 202 (18.5) 13 (13.8) 189 (18.9)
Having ever heard of b* 81 (7.4) 9 (9.6) 72 (7.2)
Having ever heard of a* 350 (32) 20 (21.3) 330 (33)
Being considered monkeypox vaccine is better for people living with HIV 0.001
No 200 (18.3) 24 (25.6) 176 (17.7)
Uncertain 416 (38.1) 46 (48.9) 370 (37)
Yes 477 (43.6) 24 (25.5) 453 (45.3)
Worries about MPX
Worried about the potential pandemic in mainland China 0.007
No 292 (29.9) 22 (25.6) 270 (30.3)
Yes 323 (33) 19 (22.1) 304 (34.1)
I do not know 362 (37.1) 45 (52.3) 317 (35.6)
Worried about being infected with MPXV 0.032
No 373 (34.1) 33 (35.1) 340 (34)
Yes 364 (33.3) 21 (22.3) 343 (34.3)
I do not know 356 (32.6) 40 (42.6) 316 (31.6)
Worried about having sequelae after infected MPX 0.004
No 90 (8.2) 10 (10.6) 80 (8)
Yes 639 (58.5) 40 (42.6) 599 (60)
I do not know 364 (33.3) 44 (46.8) 320 (32)
Attitudes about monkeypox vaccination
Being considered monkeypox vaccine is safety <0.001
No 95 (8.7) 16 (17) 79 (7.9)
Yes 746 (68.2) 37 (39.4) 709 (71)
Do not know 252 (23.1) 41 (43.6) 211 (21.1)
Being considered the necessity for smallpox/monkeypox vaccination promotion in China <0.001
No 64 (5.9) 32 (34) 32 (3.2)
Yes 1,029 (94.1) 62 (66) 967 (96.8)
Being considered smallpox/monkeypox vaccine should be prioritized for MSM 0.040
Disagree 107 (9.8) 14 (14.9) 93 (9.3)
Unsure 325 (29.7) 34 (36.2) 291 (29.1)
Agree 661 (60.5) 46 (48.9) 615 (61.6)
Willingness to encourage male friends or sexual partners to get vaccinated against MPX <0.001
Unwilling 60 (5.5) 33 (35.1) 27 (2.7)
Willing 1,033 (94.5) 61 (64.9) 972 (97.3)
Willingness to receive monkeypox or smallpox vaccination when most of your friends or sexual partners have been vaccinated <0.001
Unwilling 49 (4.5) 31 (33) 18 (1.8)
Willing 1,044 (95.5) 63 (67) 981 (98.2)
Behaviors
Number of anal sex partners in the past 3 months <0.001
0 159 (24.1) 14 (26.4) 145 (23.9)
1–5 454 (68.9) 28 (52.8) 426 (70.3)
>6 46 (7) 11 (20.8) 35 (5.8)
Frequency of oral sex in the past 3 months 0.005
3 times or below per month 343 (68.6) 18 (46.2) 325 (70.5)
4–6 times per week 95 (19) 14 (35.9) 81 (17.6)
4 times or above per week 62 (12.4) 7 (17.9) 55 (11.9)
Frequency of condom use in the past 3 months 0.056
never 21 (4.2) 4 (10.3) 17 (3.7)
1–39% 23 (4.6) 4 (10.3) 19 (4.1)
40–60% 52 (10.4) 6 (15.4) 46 (10)
61–99% 125 (25) 7 (17.9) 118 (25.6)
100% 279 (55.8) 18 (46.2) 261 (56.6)
Having ever uptake of smallpox vaccine at birth 0.001
No 247 (22.6) 34 (36.2) 213 (21.3)
Yes 846 (77.4) 60 (63.8) 786 (78.7)
Having ever uptake monkeypox/smallpox vaccine in the last year 0.776
No 718 (65.7) 63 (67) 655 (65.6)
Yes 375 (34.3) 31 (33) 344 (34.4)

*a, Smallpox vaccine (ACAM2000); b, JYNNEOS, a monkeypox vaccine certified by the US Medicine and Drug Administration in 2019. MSM, men who have sex with men; HIV, human immunodeficiency virus; STDs, Sexually transmitted diseases.