Fig 2.
Swine-origin A(H3N2) virus replication in ferret tissues. Three naïve ferrets (6–9 months old) each were intranasally inoculated with 6.0 log10 PFU of viruses and ferret blood or tissues including nasal turbinate (Nasal Tur), trachea, lung, brain (pooled from both anterior and posterior sections), olfactory bulb (OB), kidney, spleen, liver, and intestine (pooled from duodenum, jejunoileal loop, and descending colon) were collected on day 3 p.i. for viral titer determination in MDCK cells by standard plaque assay. Viral titers are expressed at log10 PFU per ml (for nasal turbinate, olfactory bulb) or per gram of tissue. Dashed line indicates the limit of detection (1 log10 PFU/ml or g).