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. 2024 Feb 20;14:104. doi: 10.1038/s41398-024-02815-0

Fig. 1. Increased motor activity and impaired recognition and spatial memory for Fmr1 KO rats.

Fig. 1

Spontaneous and habituated horizontal and vertical motor activity for Fmr1 WT (n = 12) and KO (n = 12) rats in the open field apparatus. Distance traveled (a) and vertical counts (b) during spontaneous motor activity. Distance traveled (c) and vertical counts (d) during habituated motor activity. Time spent in the center of the open-field apparatus (e). Habituation to Learning (f) of Fmr1 WT and KO rats. Assessment of recognition and spatial short-term memory of Fmr1 WT and KO rats. Discrimination Index (DI) of Fmr1 WT (n = 10) and KO rats (n = 12) for the Novel Object Recognition Task (NORT) (g). Total time spent exploring the two objects during the test phase (T2) of the test (h). Discrimination index (DI) of Fmr1 WT (n = 9) and KO rats (n = 11) for the Novel Object Location Task (NOLT) (i). Total time spent exploring the two objects in the test phase (T2) of the test (j). All results are represented as means ± SEM; *P < 0.05, **P < 0.01, ***P < 0.001.