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. 2024 Feb 20;14:4183. doi: 10.1038/s41598-024-54084-y

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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ALDH2 inhibits viability, proliferation, migration, and invasion of melanoma cells. (A) Transfection efficiency was detected by qRT-PCR. (B) The viability of A375/SK-MEL-2 cells was measured by Cell counting Kit-8 assay. (C) The proliferation was detected by 5-Ethynyl-2′-deoxyuridine assay. (D) The migration of A375/SK-MEL-2 cells was measured by wound healing assay. (E) The invasion of A375/SK-MEL-2 cells was measured by Transwell assay. ^***P < 0.001 versus pcDNA3.1-NC group.