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. 2024 Feb 7;15:1343029. doi: 10.3389/fmicb.2024.1343029

Figure 6.

Figure 6

Genetic context approach illustrated using the example of neighboring genes SCO1206 and SCO1207 in Streptomyces coelicolor. SCO1206 encodes 1,3,6,8-tetrahydroxynaphthalene synthase, while SCO1207 encodes Biflaviolin synthase CYP158A2. The figure highlights the structural similarity between naphthalene-1,3,6,8-tetrol, a product of the reaction catalyzed by 1,3,6,8-tetrahydroxynaphthalene synthase, and flaviolin, the substrate of the protein encoded by the adjacent gene, Biflaviolin synthase CYP158A2.