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. 2024 Feb 7;12:1344060. doi: 10.3389/fcell.2024.1344060

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Copyright © 2024 Zhang and Xie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Exosomal ferroptosis-related ncRNAs for treatment of AF, IBD, MS, IDD, and sepsis-induced lung injury. The injection of exosomes carrying the aforementioned ncRNAs holds promise as a therapeutic intervention to prevent cell death mediated by ferroptosis. These exosomes, enriched with specific ncRNAs, can effectively suppress the expression of ferroptosis inducer genes. By doing so, they contribute to the inhibition of ferroptosis, ultimately facilitating a reversal of the pathological conditions.