Figure 5.

Unsupervised clustering of Gastric Muscularis Propria macrophages

(A) Unsupervised clustering of HLA-DR+CD14⁺ cells reveal 17 distinct clusters.

(B) Bubble plot demonstrating Z score expression of selected genes in 17 clusters (color) as well as percentage of cells expressing the genes (size).

(C) Bubble plot showing Z score expression of selected genes associated with embryonic-derived macrophages in the 17 clusters (color) as well as percentage of cells expressing the genes (size).

(D) Statistically significant Gene Ontology enrichment terms for canonical genes in clusters 7, 8 and 14.

(E) Clusters 3, 6 and 16 are overrepresented by cells from gastroparesis (blue) samples than controls (red, FDR<0.05 for all three).

See also Table S8.