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. 2024 Feb 16;101:105009. doi: 10.1016/j.ebiom.2024.105009

Table 2.

Average dosage (in milligrams|) administered per index drug, presented as mean and standard deviation.

First index drug Average dose (SD)
Antidepressants Sertraline PGx-guided = 86 Control = 92
78.55 (43.42) 96.74 (35.4)
Venlafaxine PGx-guided = 75 Control = 98
180.2 (76.3) 182.14 (61.87)
Escitalopram PGx-guided = 85 Control = 68
12.24 (5.09) 14.45 (5.05)
Citalopram PGx-guided = 71 Control = 41
19.51 (8.5) 19.02 (8.53)
Paroxetine PGx-guided = 16 Control = 7
21.25 (8.06) 24.29 (5.35)
Amitriptyline PGx-guided = 16 Control = 4
20.56 (25.48) 65 (48.13)
Clomipramine PGx-guided = 6 Control = 5
167.92 (66.9) 150 (53.03)
Antipsychotics Haloperidol PGx-guided = 64 Control = 133
20.84 (12.41) 22.19 (14.8)
Aripiprazole PGx-guided = 110 Control = 72
21.68 (37.53) 20.66 (8.67)
Zuclopenthixol PGx-guided = 13 Control = 8
42.54 (13.37) 61.88 (26.72)

Note: Carbamazepine, Pimozide and Doxepine are not included in the table (Carbamazepine was removed from PREPARE's list of index drugs and was only prescribed to 3 patients, all in the PGx-guided arm, while Pimozide and Doxepine were only prescribed in one patient each).