Table 7.
Number of patients under psychiatric polypharmacy.
| Entire patient cohort | Control N = 529a | PGx-guided N = 547a | p-valueb |
|---|---|---|---|
| At least 4 psychiatric drugs | 143 (27.03%) | 124 (22.67%) | 0.2b |
| Less than 4 psychiatric drugs | 291 (55.01%) | 310 (56.67%) | |
| Only index drug (No co-administered drugs) | 95 (17.96%) | 113 (20.66%) | |
| Average number of co-administered psychiatric drugs on top of index drug | 2 (1–4) | 2 (1–3) | 0.021c |
|
Actionable cohort |
Control N = 126a |
PGx-guided N = 136a |
p-valueb |
| At least 4 psychiatric drugs | 29 (23.02%) | 28 (20.59%) | 0.8b |
| Less than 4 psychiatric drugs | 69 (54.76%) | 74 (54.41%) | |
| Only index drug (No co-administered drugs) | 28 (22.22%) | 34 (25.00%) | |
| Average number of co-administered psychiatric drugs on top of the index drug | 2 (1–3) | 2 (0.75–3) | 0.8c |
a
n (%); Median (IQR).
b
Pearson's Chi-squared test.
c
Wilcoxon rank sum test.