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. 2024 Feb 6;27(3):109152. doi: 10.1016/j.isci.2024.109152

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© 2024 The Author(s)

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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PCID2 interacts with proteins involved in multiple stages of RNA processing

(A) IP-western blot of PCID2-Flag in control and stably PCID2-Flag expressing J-Lat 11.1 samples for subsequent mass spectrometry analysis.

(B) Venn diagram of the total individual and common number of identified hits by mass spectrometry in PCID2-Flag over control samples from two independent IP-MS runs.

(C) Network of PCID2 interacting hits identified by mass spectrometry. Hits are classified by cellular function. Gray lines represent PCID2 interacting proteins as analyzed by IP-MS in this study. Red lines represent protein-protein interactions predicted by STRING analysis on experimental evidence only.