5. Sensitivity analysis—blinding.
Study ID | Arm removed | Analyses affected |
Bateman 2013 [SHINE] | Tiotropium 18 mcg | SGRQ6m, FEV6m |
Donohue 2010 [INHANCE] | Tiotropium 18 mcg | SGRQ6m, FEV6m |
GLOW2 2012 | Tiotropium 18 mcg | SGRQ6m, FEV6m, SGRQ12m, FEV12m |
SPARK 2013 | Whole study (2 arms) | SGRQ6m, FEV6m, SGRQ12m, FEV12m |
Vogelmeier 2008 | Tiotropium 18 mcg | Did not appear in analyses |
FEV = forced expiratory volume in one second
SGRQ = St George's Respiratory Questionnaire
6m = six month analysis
12m = 12 month analysis