Figure 2.
Cell viability in human tissue organoids treated with AFB1, AAI, and PhIP. Organoids from normal human stomach (A, C, and E; D95 and D88), liver (B; D4 undifferentiated and differentiated), kidney (D; D50 and D21), and colon (F; D351 and D311) tissues were treated with various concentrations of AFB1 (A, B), AAI (C, D), and PhIP (E, F) for 48 h. Vehicle controls DMSO (A, B, E, and F) or water (C, D) were included. Cell viability (% control) was measured using the CellTiter-Glo assay. Results are shown as mean ± SD (n ≥ 3).