Table 3. Comparison of treatment outcomes and parameters in IVF/ICSI cycles using standard treatment vs. EmbryoGlue®.
#Independent t-test, morphology grading: excellent (3AA,4AA,5AA), good (3,4,5,6 AB or BA), average (3,4,5,6 BB or AC or CA), poor (3,4,5,6 BC or CC).
| Variables | Standard treatment (n=649) | EmbryoGlue® (n=649) | P-value |
| Endometrial thickness at the day of P start, mm (mean ± SD) | 8.94±1.24 | 9.05±1.00 | 0.079# |
| Duration of progesterone administration, n (%) | 0.808 | ||
| Day 6 | 612(94.3%) | 614(94.6%) | |
| Day 7 | 37(5.7%) | 35(5.4%) | |
| Number of blastocysts transferred n (%) | 0.298 | ||
| 1 | 97(14.9%) | 84(12.9%) | |
| 2 | 552(85.1%) | 565(87.1%) | |
| Blastocyst morphology of SET, n (%) | 0.071 | ||
| Excellent + good | 89(91.8%) | 83(98.8%) | |
| Average | 3(3.1%) | 1(1.2%) | |
| Poor | 5(5.2%) | 0(0%) | |
| Blastocyst morphology of DET (first embryo), n (%) | 0.179 | ||
| Excellent + good | 529(95.8%) | 549(97.2%) | |
| Average | 20(3.6%) | 16(2.8%) | |
| Poor | 3(0.5%) | 0(0%) | |
| Blastocyst morphology of DET (second embryo), n (%) | 0.200 | ||
| Excellent + good | 487(88.2%) | 507(89.7%) | |
| Average | 56(10.1%) | 55(9.7%) | |
| Poor | 9(1.6%) | 3(0.5%) | |
| βHCG rate, n/n (%) | 406/649(62.6%) | 494/649(76.1%) | <0.001 |
| Biochemical loss rate, n/n (%) | 32/406(7.9%) | 43/494(8.7%) | 0.657 |
| Clinical pregnancy rate, n/n (%) | 373/649(57.6%) | 451/649(69.5%) | <0.001 |
| Clinical miscarriage rate, n/n (%) | 65/373(17.4%) | 58/451(12.9%) | 0.067 |
| Live birth rate, n/n (%) | 308/649(47.5%) | 393/649(60.6%) | <0.001 |
| Multiple live birth rate, n/n (%) | 100/649(15.4%) | 132/649(20.3%) | 0.021 |