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. 2024 Feb 7;12:1309401. doi: 10.3389/fpubh.2024.1309401

Table 5.

The interaction between IADL limitation and cognitive impairment on depression.

Variables OR (95%CI) aOR (95%CI)
Additive interaction
IADL limitation(no) - cognitive impairment(no) 1.00(reference) 1.00(reference)
IADL limitation(yes) - cognitive impairment(no) 2.13(1.94–2.35) *** 2.12(1.82–2.47) ***
IADL limitation(no) - cognitive impairment(yes) 2.98(1.29–6.92) * 1.74(0.35–8.67)
IADL limitation(yes) - cognitive impairment(yes) 3.52(3.06–4.05) *** 3.67(2.88–4.66) ***
Relative excess risk due to interaction 18.28(1.07–35.50) 10.71(−9.09–30.50)
Attributable proportion 0.82(0.76–0.87) 0.79(0.64–0.94)
Synergy index 6.87(5.70–8.28) 6.73(4.73–9.59)
Multiplicative interaction
BADL limitation× cognitive impairment 0.55(0.24–1.30) 0.99(0.20–4.98)

Abbreviation: OR, odds ratio; aOR, adjusted odds ratio; CI, confidence interval. a Adjusting for age, sex, residence, living arrangement, education level, marital status, annual income, occupation, smoking status, drinking status, exercise, sleep duration, and chronic disease.

*p < 0.05 **p < 0.01 ***p < 0.001.