Fig. 4.

Repartition of TMB scores according to tumor types using the algorithm of the Institut Curie (IC). Tumor types with less than n = 5 samples were groups into “Others” in this plot which comprise the following tumor types: cutaneous melanoma, sex chord tumor, appendix, esophageal, salivary gland tumor, UCNT, GIST, neuroendocrine, renal, vulva, craniopharyngioma, cutaneous SCC, duodenal carcinoma, hepatoblastoma, leiomyosarcoma, peritoneum, small bowel carcinoma, thymoma, and Waldenstrom. HNSCC, head and neck squamous cell carcinoma; CNS, central nervous system; ACUP, adenocarcinoma of unknown primary; TMB, tumor mutational burden