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. Author manuscript; available in PMC: 2024 Feb 21.
Published in final edited form as: J Neurooncol. 2019 Sep 3;145(1):23–34. doi: 10.1007/s11060-019-03275-z

Fig. 2.

Fig. 2

miR-29a inhibits GBM cell and GSC proliferation, induces GBM cell apoptosis and inhibits GBM cell migration and invasion. a Proliferation assay showing the inhibition of GBM cell U87 and GSC-267 proliferation by pre-miR-29a. b miR-29a inhibitor (anti-miR-29a) transfection enhances GBM cell A172 and U87 proliferation. c, d AnnexinV-PE and 7-AAD flow-cytometric analysis of GBM cells U87 (c) and A172 (d) showing induction of apoptosis after pre-miR-29a transfection. e GBM cells A172 were transfected with either Pre-miR-29a or controls and assessed for migration with the wound healing assay. f Pre-miR-29a or control-transfected A172 cells were used in a transwell invasion assay. The left panel shows a representative invasion assay, the right panel shows the quantification of invading cells. The data show that miR-29a overexpression inhibits GBM cell migration and invasion. *P < 0.05