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. 2023 Dec 4;15(2):519–538. doi: 10.1039/d3md00585b

Hydrogen bond distance of isoquinolinones into the alternative site of yeast α-glucosidase.

Compound Hydrogen bond distance (Å)
Glu304 Other amino acid
(R)-10b 2.6 (His63)
(S)-10b 3.2
(R)-10e 2.2 2.1 (Asn241)
2.7 (Arg312)
(S)-10e 2.3 (Arg222)
2.7 (Trp242)
(R)-10o 2.5 (His239)
(S)-10o 3.3 3.1 (Thr307)