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. Author manuscript; available in PMC: 2024 Feb 21.
Published in final edited form as: Peptides. 2022 Jan 19;151:170748. doi: 10.1016/j.peptides.2022.170748

Figure 1: Species difference between rodent and primate islet expression of Ucn3 and Crh.

Figure 1:

The expression of two sets of genes, Mafa/Mafb and Ucn3/Crh, that markedly differ in their expression between alpha and beta cells in mouse (A) and human (B) islets. Mafa is restricted to beta cells of both species, while Mafb is selectively expressed in mouse alpha cells (A) but expressed in human beta cells as well (B). Ucn3 is highly selective for mouse beta cells while Crh is detected in neither mouse islet population (A, C, D). By contrast, UCN3 expression is abundant in human alpha and beta cells, while CRH is enriched in human alpha cells (B, E, F). Human RNA-seq data from [78]. Figure originally published in [16] under a Creative Commons Attribution 4.0 International License and reused without alteration.