Figure 3. Risk of Aggressive Prostate Cancer (PCa) Associated With Rare Deleterious Variants in Candidate PCa Genes.

A, Genes with nominal P values (P < .05). B, Genes with large effect sizes (odds ratio [OR] ≥2) but nonsignificant P values (P > .05). C, Genes with low evidence (P > .05 and OR <2). Red font represents potentially novel candidate PCa DNA repair genes with positive associations. Error bars indicate 95% CIs, which are reported in Table 2.