Table 1.
The comparison of clinical features and DHT, PGD2, TGF-β1 between AGA and control.
| Variable | AGA (n = 83) | Control (n = 84) | P-value |
|---|---|---|---|
| Sex | 0.565 | ||
| Male, n (%) | 53 (63.86%) | 50 (59.52%) | |
| Female, n (%) | 30 (36.14%) | 34 (40.48%) | |
| Age | 28.14 ± 7.25 | 27.71 ± 5.13 | 0.968 |
| Male, year | 30.15 ± 7.01 | 29.04 ± 5.19 | 0.361 |
| Female, year | 24.6 ± 6.34 | 25.76 ± 4.45 | 0.089 |
| WC, cm | 86.25 ± 12.81 | 80.99 ± 8.77 | 0.002 |
| BMI, kg/m2 | 24.31 ± 4.07 | 22.09 ± 2.52 | 0.000 |
| SBP, mmHg | 123.81 ± 15.75 | 117.82 ± 12.64 | 0.007 |
| DBP, mmHg | 78.80 ± 13.80 | 77.39 ± 8.66 | 0.434 |
| FBG, mmol/L | 4.87 ± 0.47 | 4.85 ± 0.62 | 0.419 |
| CHOL, mmol/L | 4.32 ± 0.88 | 4.50 ± 0.76 | 0.055 |
| HDL-C, mmol/L | 1.12 ± 0.28 | 1.24 ± 0.31 | 0.007 |
| LDL-C, mmol/L | 2.48 ± 0.80 | 2.41 ± 0.63 | 0.820 |
| TG, mmol/L | 1.32 ± 0.90 | 1.21 ± 1.03 | 0.214 |
| Incidence of MetS, n (%) | 22 (26.51%) | 10 (11.90%) | 0.017 |
| DHT, pg/ml | 1159.49 ± 250.69 | 1033.29 ± 204.14 | 0.000 |
| PGD2, pg/ml | 714.48 ± 302.19 | 607.30 ± 281.68 | 0.044 |
| TGF-β1, ng/ml | 19.32 ± 6.04 | 15.77 ± 3.72 | 0.000 |
AGA: Androgenetic alopecia, WC: Waist circumference, BMI: Body mass index, SBP: Systolic blood pressure, DBP: Diastolic blood pressure, FBG: Fasting blood glucose, CHOL: Cholesterol, TG: Triglyceride, LDL-C: Low density lipoprotein cholesterol, HDL-C: High density lipoprotein cholesterol, MetS: Metabolic syndrome, DHT: Dihydrotestosterone, PGD2: Prostaglandin D2, TGF-β1: Transforming growth factor-β1.