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(A) Scheme of cartilage defect modeling and treatment protocol. (B) Gross observation of femur cartilage after treatment at 5 and 10 weeks (scale bars 2 mm). (C) Heat map of ICRS macroscopic assessment of cartilage at 5 and 10 weeks. (D) Roughness parameter of the cartilage surface regeneration zone at10 weeks after treatment. (E) The AFM images of the cartilage surface regeneration zone at10 weeks after treatment (10 × 10 mm).
