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. 2024 Feb 21;15:907. doi: 10.1038/s41467-024-45107-3

Fig. 1. Patient recruitment and characteristics.

Fig. 1

a Diagram showing the procedure followed to recruit adjudicated Post-infectious Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (PI-ME/CFS) and matched healthy volunteers (HV) and measurements undertaken for deep phenotyping of the cohorts. The number of participants at each stage of recruitment are noted. b Comparisons of age, sex, and BMI distribution in HV (blue; n = 21 independent participants) and PI-ME/CFS (red; n = 17 independent participants) using unadjusted two-sided t-tests for independent samples. c Distribution of the response of HV (blue; n = 21 independent participants) and PI-ME/CFS (red; n = 17 independent participants) to the indicated patient reported outcome questionnaires. Group comparisons performed using unadjusted two-sided Mann–Whitney-U tests. CSF cerebrospinal fluid, PBMC peripheral blood mononuclear cell, BMI body mass index, PROMIS Patient-Reported Outcomes Measurement Information System, PHQ-15 Patient Health Questionnaire – 15, MASQ Multiple Ability Self-Report Questionnaire. Figure 1A created with Biorender.com. Source data are provided as a Source Data file.