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. 2024 Feb 22;14:4344. doi: 10.1038/s41598-024-54663-z

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Whole brain volume analysis in a 42 healthy control by the DLS method and Freesurfer with manual correction. (A) Whole brain volume of overall healthy controls (B) Whole brain volume of healthy controls with age ≤ 2 years (C) Whole brain volume of healthy controls with 2 < age ≤ 6 (D) Whole brain volume of healthy controls with age > 6 The blue dots showed the volume measured by Freesurfer with manual correction; The red dots showed the volume measured by the DLS method. **p-values < 0.001.