Table 1.
Overview of ASFV RNAP subunits and comparison with RNAPII and VACV RNAP
| Subunit classification | ASFV Gene ID | ASFV RNAP | Yeast RNAPII | VACV RNAP |
|---|---|---|---|---|
| Catalytic core | NP1450L | vRPB1 | RPB1 | Rpo147 |
| EP1242L | vRPB2 | RPB2 | Rpo132 | |
| Assembly platform | H359L | vRPB3-11 | RPB3 | Rpo35 |
| RPB11 | ||||
| CP80R | vRPB10 | RPB10 | Rpo7 | |
| – | – | RPB12 | – | |
| Auxiliary function | – | – | RPB4 | – |
| D205R | vRPB5 | RPB5 | Rpo22 | |
| C147L | vRPB6 | RPB6 | Rpo19 | |
| D339La | vRPB7 | RPB7 | Rpo18 | |
| – | – | RPB8 | – | |
| C105R | vRPB9 | RPB9 | – | |
| – | – | – | Rpo30 |
Summarised from Cackett et al. 13.
aThe N-terminal part of ASFV D339L is homologous to RNAPII RPB7 and VACV Rpo18 stalk subunits.