Table 2.

Most common post COVID-19 symptoms (n = 2539)

	Population			By COVID-19 test result
Symptom				Positive			Negative			P-value	P-value	Odds ratio
	Na	Yesb	%	Na	Yesb	%	Na	Yesb	%	Unadjusted	Adjustedc	[95% CI]
General symptoms
Fatigue/Tiredness	2281	1173	51.4	1267	754	59.5	1,014	419	41.3	<0.001	<0.001	2.15 [1.79–2.60]
Muscle & body aches	2270	724	31.9	1260	471	37.4	1,010	253	25.0	<0.001	<0.001	1.83 [1.49–2.24]
Joint pains	2269	700	30.9	1261	456	36.2	1,008	244	24.2	<0.001	<0.001	1.99 [1.62–2.46]
Shortness of breath	2272	527	23.2	1261	384	30.5	1,011	143	14.1	<0.001	<0.001	2.68 [2.13–3.39]
Cough	2263	525	23.2	1253	330	26.3	1,010	195	19.3	<0.001	<0.001	1.55 [1.25–1.94]
Brain & nervous system
Headaches	2215	977	44.1	1224	610	49.8	991	367	37.0	<0.001	<0.001	1.60 [1.32–1.94]
Concentration problems	2228	908	40.8	1236	625	50.6	992	283	28.5	<0.001	<0.001	2.64 [2.17–3.22]
Memory problems	2226	677	30.4	1233	486	39.4	993	191	19.2	<0.001	<0.001	2.65 [2.15–3.28]
General weakness	2224	487	21.9	1233	332	26.9	991	155	15.6	<0.001	<0.001	2.03 [1.61–2.57]
Dizziness	2219	452	20.4	1229	305	24.8	990	147	14.8	<0.001	<0.001	1.92 [1.52–2.43]
Balance problems	2222	419	18.9	1231	281	22.8	991	138	13.9	<0.001	<0.001	2.07 [1.62–2.66]
Mental well-being
Difficulty sleeping	2216	1,054	47.6	1234	643	52.1	982	411	41.9	<0.001	<0.001	1.42 [1.18–1.71]
Anxiety	2213	1,068	48.3	1229	628	51.1	984	440	44.7	<0.001	0.086	1.18 [0.98–1.42]
Depression	2219	775	34.9	1233	467	37.9	986	308	31.2	0.001	0.040	1.22 [1.01–1.48]
Ears, nose, and throat
Congested nose	2260	775	34.3	1251	468	37.4	1,009	307	30.4	<0.001	0.008	1.28 [1.07–1.54]
Ringing in ears	2250	494	22.0	1245	303	24.3	1,005	191	19.0	0.002	0.001	1.42 [1.15–1.76]
Heart or circulation
Irregular heartbeats	2242	447	19.9	1243	311	25.0	999	136	13.6	<0.001	<0.001	2.19 [1.73–2.80]
Leg pain when walking	2239	421	18.8	1241	287	23.1	998	134	13.4	<0.001	<0.001	2.08 [1.62–2.67]
Eyes or vision
Dry eyes	2238	585	26.1	1242	349	28.1	996	236	23.7	0.019	<0.001	1.44 [1.17–1.78]
Stomach or digestion
Heartburn (reflux)	2238	534	23.9	1237	334	27.0	1,001	200	20.0	<0.001	<0.001	1.47 [1.20–1.81]

^aResponder (Reported yes symptom or no symptom).

^bN Reported patient with symptom.

^cP-Value calculation by Logistic Regression adjusted for age, sex, BMI, vaccine status, race/ethnicity, CCI, and time after COVID-19 test, respectively. See Supplementary Fig. 2 for a graphical representation of odds ratio and 95% confidence interval.