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. 2024 Feb 21;4:24. doi: 10.1038/s43856-024-00440-y

Table 5.

Frequently reported symptoms by race (n = 2539)

White/Caucasian (n = 2060) Non-White/Non-Caucasian (n = 479)a Comparisonb
All By COVID-19 test result All By COVID-19 test result
Symptom Positive Negative Odds Ratio Positive Negative Odds Ratio P-value P-value
% Nc % Nc % [95% CI] % Nc % Nc % [95% CI] Unadjusted Adjustedd
General symptoms
   Fatigue/Tiredness 51.4 681 58.8 377 42.4 1.96 [1.61–2.38] 48.0 147 61.5 83 36.2 3.12 [2.05–4.80] 0.897 0.640
   Muscle & body aches 30.3 401 34.8 224 25.2 1.59 [1.29–1.98] 35.1 112 46.5 56 24.6 2.84 [1.83–4.47] 0.008 0.642
   Joint pains 30.2 406 35.3 217 24.5 1.85 [1.49–2.30] 28.6 91 37.8 46 20.2 2.99 [1.88–4.85] 0.910 0.756
   Shortness of breath 23.2 347 30.1 130 14.7 2.50 [1.96–3.21] 22.8 81 33.9 28 12.2 3.98 [2.40–6.77] 0.719 0.677
   Cough 22.0 283 24.7 171 19.3 1.40 [1.11–1.77] 24.4 74 30.8 43 18.9 2.11 [1.32–3.41] 0.276 0.405
Brain & nervous system
   Headaches 42.3 550 49.0 321 36.7 1.49 [1.21–1.82] 42.8 123 53.7 82 37.6 1.97 [1.29–3.05] 0.641 0.148
   Concentration problems 39.6 565 49.9 250 28.5 2.49 [2.03–3.07] 38.2 123 53.2 60 27.6 3.13 [2.02–4.90] 0.841 0.951
   Memory problems 29.4 435 38.5 170 19.4 2.48 [1.99–3.10] 30.1 99 42.9 45 20.7 2.83 [1.80–4.51] 0.669 0.888
   General weakness 20.6 292 25.8 132 15.1 1.96 [1.53–2.52] 24.0 77 33.5 38 17.5 2.51 [1.55–4.13] 0.125 0.972
   Dizziness 19.4 266 23.6 134 15.3 1.64 [1.28–2.11] 20.7 66 28.7 33 15.1 2.41 [1.44–4.10] 0.442 0.200
   Balance problems 18.3 250 22.2 128 14.6 1.78 [1.38–2.31] 17.3 54 23.5 29 13.5 2.46 [1.43–4.34] 0.980 0.709
Mental well-being
   Difficulty sleeping 46.1 578 51.2 371 42.7 1.29 [1.06–1.57] 44.3 127 54.7 85 39.7 1.74 [1.15–2.66] 0.815 0.978
   Anxiety 46.3 568 48.8 385 44.3 1.11 [0.90–1.36] 44.1 123 53.5 88 41.3 1.43 [0.92–2.21] 0.638 0.086
   Depression 33.8 423 37.5 274 31.5 1.19 [0.96–1.48] 32.4 91 39.6 64 29.6 1.28 [0.82–2.01] 0.949 0.840
Ears, nose, and throat
   Congested nose 34.3 417 36.5 289 32.6 1.16 [0.95–1.42] 31.5 94 39.7 57 25.1 1.99 [1.29–3.10] 0.835 0.724
   Ringing in ears 22.1 279 24.5 177 20.1 1.33 [1.06–1.68] 20.0 60 25.4 36 15.9 1.90 [1.15–3.18] 0.994 0.706
Heart or circulation
   Irregular heartbeats 19.3 270 23.7 127 14.4 1.85 [1.44–2.38] 19.4 68 29.1 25 11.3 3.57 [2.10–6.27] 0.384 0.912
   Leg pain when walking 16.5 232 20.4 108 12.3 1.94 [1.48–2.56] 24.0 78 33.3 37 17.0 2.40 [1.48–3.95] <0.001 0.026
Eyes or vision
   Dry eyes 25.9 310 27.3 224 25.5 1.25 [1.00–1.56] 22.8 72 30.6 37 16.7 2.65 [1.62–4.38] 0.788 0.118
Stomach or digestion
   Heartburn (reflux) 23.7 308 27.2 180 20.5 1.35 [1.08–1.70] 21.3 63 27.3 39 17.5 2.13 [1.29–3.59] 1.000 0.821

aNon-white/Non-Caucasian categorized as American Indian/Alaskan Native (n = 17), Asian (n = 46), Black/African American (n = 27), Native Hawaiian/Other Pacific Islander (n = 45), Other (n = 344).

bWhite/Caucasian with a positive COVID-19 test result versus Non-White/Non-Caucasian with a positive Covid-19 test result.

cN Reported patient with symptoms.

dAdjusted P-Value for comparing white and non-white COVID-positive patients calculated from Logistic Regression after the adjustment of age, sex, BMI, vaccine status, race/ethnicity, CCI, and time after COVID-19 test.