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. 2024 Feb 21;4:24. doi: 10.1038/s43856-024-00440-y

Table 7.

Frequently reported symptoms by time between testing and survey receipt (n = 2539)

3–9 months (n = 765) 10–12 months (n = 1073) More than 12 months (n = 701)
COVID-19 test result COVID-19 test result COVID-19 test result
Symptomw Positive Negative Odds Ratio Positive Negative Odds ratio Positive Negative Odds ratio
Na % Na % [95% CI] Na % Na % [95% CI] Na % Na % [95% CI]
General symptoms
   Fatigue/Tiredness 247 58.7 129 38.4 2.29 [1.64–3.21] 422 60.9 173 46.8 1.78 [1.34–2.35] 159 56.2 159 38.4 2.25 [1.59–3.20]
   Muscle & body aches 167 39.7 83 24.9 2.11 [1.48–3.03] 240 34.9 95 25.7 1.52 [1.12–2.07] 106 37.5 102 24.6 1.82 [1.25–2.65]
   Joint pains 158 37.5 80 24.1 2.12 [1.48–3.04] 238 34.6 85 23.0 1.83 [1.34–2.52] 101 35.7 98 23.7 2.24 [1.52–3.32]
   Shortness of breath 130 30.8 56 16.7 2.14 [1.46–3.17] 211 30.6 55 14.9 2.43 [1.72–3.46] 87 31.0 47 11.4 4.16 [2.65–6.65]
   Cough 118 28.2 62 18.5 1.49 [1.01–2.21] 170 24.8 66 17.9 1.57 [1.12–2.21] 69 24.6 87 21.0 1.25 [0.82–1.89]
Brain & nervous system
   Headaches 207 50.1 116 35.4 1.74 [1.24–2.44] 328 49.2 150 41.6 1.32 [0.99–1.75] 138 50.5 138 34.2 1.69 [1.17–2.44]
   Concentration problems 210 50.2 99 30.1 2.70 [1.92–3.83] 343 51.2 107 29.6 2.49 [1.86–3.36] 135 48.9 105 26.0 2.58 [1.79–3.74]
   Memory problems 173 41.6 69 20.9 2.98 [2.08–4.32] 264 39.4 75 20.8 2.41 [1.76–3.33] 97 35.3 71 17.6 2.26 [1.53–3.37]
   General weakness 122 29.3 54 16.5 2.06 [1.39–3.09] 178 26.6 55 15.2 2.17 [1.53–3.14] 69 25.1 61 15.1 1.83 [1.18–2.84]
   Dizziness 104 25.1 56 17.0 1.56 [1.04–2.34] 165 24.8 53 14.7 1.90 [1.33–2.74] 63 22.7 58 14.4 1.73 [1.12–2.68]
   Balance problems 99 24.1 55 16.8 1.89 [1.25–2.87] 158 23.5 44 12.2 2.37 [1.61–3.54] 47 17.0 58 14.4 1.57 [0.97–2.53]
Mental well-being
   Difficulty sleeping 219 52.8 131 39.7 1.67 [1.20–2.32] 342 51.0 158 44.3 1.21 [0.91–1.60] 144 52.4 167 42.2 1.30 [0.91–1.84]
   Anxiety 216 51.9 138 41.9 1.55 [1.09–2.20] 333 50.0 174 48.7 0.92 [0.69–1.24] 142 51.8 162 40.8 1.26 [0.88–1.80]
   Depression 173 41.8 99 29.9 1.90 [1.34–2.72] 253 37.7 122 34.0 1.07 [0.79–1.46] 88 32.1 117 29.5 0.91 [0.62–1.34]
Ears, nose, and throat
   Congested nose 180 43.0 95 28.4 1.81 [1.29–2.55] 240 35.2 125 33.8 1.09 [0.82–1.45] 91 32.4 127 30.9 1.02 [0.71–1.47]
   Ringing in ears 104 24.9 69 21.4 1.30 [0.89–1.92] 163 24.1 72 19.6 1.23 [0.88–1.72] 72 25.6 73 17.8 1.91 [1.27–2.90]
Heart or circulation
   Irregular heartbeats 96 23.0 41 12.5 2.42 [1.57–3.89] 172 25.5 51 13.9 1.95 [1.37–2.81] 70 25.1 61 15.0 1.85 [1.21–2.85]
   Leg pain when walking 102 24.6 50 15.2 2.13 [1.41–3.27] 153 22.6 45 12.3 2.11 [1.45–3.14] 55 19.8 50 12.3 1.70 [1.05–2.77]
Eyes or vision
   Dry eyes 123 29.6 80 24.2 1.63 [1.13–2.36] 185 27.2 96 26.4 1.11 [0.81–1.53] 74 26.9 85 20.8 1.72 [1.15–2.58]
Stomach or digestion
   Heartburn (reflux) 120 28.9 62 18.7 1.82 [1.25–2.67] 178 26.4 73 19.9 1.45 [1.04–2.02] 73 26.4 84 20.7 1.17 [0.78–1.76]

aResponder (Reported yes symptom); Odds ratio and 95% confidence interval by Logistic Regression adjusted for age, sex, BMI, vaccine status, race/ethnicity, CCI, and time after COVID-19 test, respectively.