Table 2.
Independent effect of adult obesity and childhood obesity on the risk of DN using MVMR.
| OR (95% CI) | P-value | |
|---|---|---|
| Model 1 | ||
| adult BMI | 1.15 (0.96-1.37) | 0.140 |
| childhood BMI | 1.90 (1.60-2.25) | <0.001※ |
| Model 2 | ||
| adult WHR | 1.03 (0.81-1.31) | 0.796 |
| childhood BMI | 1.80 (1.40-2.31) | <0.001※ |
Model 1: independent effect of adult BMI and childhood BMI on DN; Model 2: independent effect of adult WHR and childhood BMI on DN; Asterisks (※) denote statistical significance survived false discovery rate (FDR) correction (PFDR<0.05).
BMI, body mass index; WHR, waist-to-hip ratio; DN, diabetic nephropathy; OR, odds ratio; 95%CI, 95% confidence interval.