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. 2024 Feb 8;15:1255577. doi: 10.3389/fimmu.2024.1255577

Table 4.

Rank probability or Surface Under the Cumulative Ranking (SUCRA) values for interventions.

P-A N-I Ave-A N-C P-L S Inference
aOverall survival (%) 40.2 19.7 25.3 14.9 0.0 P-A>N-C>N-I>P-L>S
aProgression-free survival (%) 8.4 5.3 8.1 21.1 57.1 0.0 P-L>N-C>P-A=Ave-A>N-I>S
bObjrctive response rate (%) 45.3 22.0 62.7 74.1 95.8 0.0 P-L>N-C>Ave-A>P-A>N-I>S
bComplete response (%) 60.2 96.1 34.5 32.2 75.0 2.1 N-I>P-L>P-A>Ave-A=N-C>S
bPartial response (%) 47.8 20.0 80.5 86.7 64.7 0.3 N-C=Ave-A>P-L>P-A>N-I>S
bOverall adverse events (%) 87.8 85.5 39.9 23.9 13.1 49.9 P-A=N-I>S>Ave-A>N-C>P-L
bAdverse events ≥3 (%) 30.5 100.0 66.1 33.9 3.0 66.4 N-I>S=Ave-A>N-C=P-A>P-L

P-A, Pembrolizumab-Axitinib; N-I, Nivolumab-Ipilimumab; Ave-A, Avelumab-Axitinib; N-C, Nivolumab-Cabozantinib; P-L, Pembrolizumab-Lenvatinib; S, Sunitinib.

a

Preferred rank probabilities of interventions for study endpoints.

b

SUCRA of interventions for study endpoints.