Table 3.
Univariable analysis of demographics for structural allograft and synthetic cage use and multivariable analysis of patient characteristics predicting synthetic cage use in 1- and 2-level ACDF.
| Univariable analysis |
Multivariable factors predictive of cage |
||||
|---|---|---|---|---|---|
| Structural allograft | Synthetic cage | p-value | OR (95% CI) | p-value | |
| N | 63,029 | 110,804 | 173,833 | ||
| Age (mean ± SD) (per decade increase) |
54.20 ± 11.47 | 55.11 ± 11.54 | p<.001 | 1.02 (1.01, 1.03) | p<.001 |
| Sex Male (%) (referent) Female (%) |
28,930 (45.9%) 34,040 (54.1%) |
49,154 (44.4%) 61,507 (55.6%) |
p<.001 | 1.04 (1.02, 1.06) | p<.001 |
| ECI (Mean ± SD) (per 2 point increase) |
3.50 ± 3.13 | 3.95 ± 3.33 | p<.001 | 1.09 (1.09, 1.10) | p<.001 |
| Region Midwest (referent) Northeast South West |
20,548 (32.6%) 11,136 (17.7%) 25,375 (40.3%) 5,723 (9.1%) |
24,582 (22.2%) 15,082 (13.6%) 55,812 (50.4%) 14,520 (13.1%) |
p<.001 | 1.11 (1.07, 1.14) 1.85 (1.81, 1.89) 2.08 (2.01, 2.16) |
p<.001 p<.001 p<.001 |
| Insurance plan Commercial (referent) Medicare Medicaid |
47,598 (75.5%) 9,361 (14.9%) 3,684 (5.8%) |
82,144 (74.1%) 18,104 (16.3%) 6,398 (5.8%) |
p<.001 | 1.00 (0.97, 1.03) 1.00 (0.96, 1.05) |
p=.944 p=.924 |
| Physician specialty Neurosurgery (referent) Orthopedics |
36,234 (57.5%) 16,433 (26.1%) |
58,713 (53.0%) 27,940 (25.2%) |
p<.001 | 1.06 (1.03, 1.08) | p<.001 |
| Number of levels treated Single-level (referent) 2-level |
44,081 (69.9%) 18,958 (30.1%) |
76,558 (69.1%) 34,268 (30.9%) |
p<.001 | 0.99 (0.97, 1.01) | p=.338 |