Table 2.

Hazard ratios (HRs) for the association of sleep duration trajectory patterns with overall cancer risk.

Sleep duration trajectory patterns		Cases/total	IRa	Crude model HR (95% CI)	P value	Adjusted modelb HR (95% CI)	P value
Overall
	Normal-stable	2235/44,844	4.80	Reference		Reference
	Increasing median-stable	299/5877	4.93	1.03 (0.91-1.16)	.67	0.97 (0.84-1.11)	.62
	Decreasing low-stable	171/2552	6.57	1.37 (1.17-1.60)	<.001	1.39 (1.16-1.65)	<.001
Age <45 years
	Normal-stable	437/17,674	2.28	Reference		Reference
	Increasing median-stable	35/1577	2.03	0.89 (0.69-1.25)	.50	0.89 (0.59-1.36)	.75
	Decreasing low-stable	31/698	4.12	1.81 (1.25-2.60)	.001	1.88 (1.30-2.71)	<.001
Age ≥45 years
	Normal-stable	1798/27,170	6.56	Reference		Reference
	Increasing median-stable	264/4300	6.08	0.93 (0.81-1.05)	.24	0.83 (0.71-1.02)	.10
	Decreasing low-stable	140/1854	7.57	1.15 (0.97-1.37)	.11	1.17 (0.96-1.42)	.12

^aIR: incidence rate per 1000 person-years.

^bThe model was adjusted for continuous (age, BMI, waist circumference, c-reactive protein, total cholesterol, triglycerides, and sleep duration in 2010) and categorical (sex, marital status, education level, sedentary time, physical activity, smoking, alcohol use, hypertension, diabetes, snoring, salt intake, and family history of tumor) variables.