Table 7. Binding Energy and Interaction of Proteins with Positive Controls, MDC, and ADC.

protein	ligand	binding energy (kcal/mol)	binding interaction
α-GD	acarbose	–4.61	ASP:69, TYR:72, HIS:112, TYR:158, ASP:215, VAL:216, LEU:219, ARG:315, ARG:446
	MDC	–3.83	TYR:158, ASP:215, ASP:216, GLN:279, HIS:280, SER:311, PRO:312, PHE:314, ARG:315, ASP:352
	ADC	–2.67	LYS:156, TYR:158, LEU:313, ARG:315, GLU:411, ASN:415
DPP-4	sitagliptin	–5.66	GLU:205, GLU:206, PHE:357, TYR:547, TRP:629, SER:630, HIS:740
	MDC	–5.30	ARG:125, HIS:126, GLU:206, SER:209, SER:630, TYR:631, VAL:656, TRP:659, TYR:666
	ADC	–4.20	TYR:553, GLN:553, LYS:554, TRP:629
MPO	salicylhydroxamic acid	–7.88	GLY:90, TYR:296, MET:87, PHE:332
	MDC	–7.79	GLU:242, ARG:333, LEU:406, LEU:417, LEU:420, ARG:424
	ADC	–7.74	GLU:102, ARG:333, LEU:217, LEU:420, ARG:424