Skip to main content
. 2024 Feb 3;9(7):8139–8150. doi: 10.1021/acsomega.3c08565

Table 3. In Vivo Pharmacokinetic Parameters for the TNF Drug, TNF-Diffused Tablet (Tenof), and TNF-SEDDS (F6) Formulation.

parameters TNF drug TNF marketed (Tenof) TNF-SEDDS (F3)
Cmax (μg/mL) 25.69 ± 2.14 148.57 ± 2.54 415.26 ± 2.11
Tmax (h) 6.15 ± 1.15 3.02 ± 1.42 1.55 ± 1.18
AUC0–72 (μg h/ml) 174.23 ± 58.18 536.41 ± 131.54 11546.64 ± 139.82
t1/2 (h) 17.25 ± 1.24 17.28 ± 1.51 17.21 ± 1.33