Table 2:
Health state utility values and event-related disutility modifiers for the UK, Japan, Spain and Italy.
| Utility or utility decrement | |||||
|---|---|---|---|---|---|
| Parameter | UK | Italy | Spain | Japan | Source |
| Health-state utility | |||||
| CKD G1 | 0.77 (0.01) | 0.85 (0.01) | 0.83 (0.01) | 0.80 (0.01) | DAPA-CKD [34] |
| CKD G2 | 0.77 (0.01) | 0.85 (0.01) | 0.83 (0.01) | 0.80 (0.01) | DAPA-CKD [34] |
| CKD G3a | 0.77 (0.01) | 0.86 (0.01) | 0.83 (0.01) | 0.80 (0.01) | DAPA-CKD [34] |
| CKD G3b | 0.77 (0.01) | 0.86 (0.01) | 0.84 (0.01) | 0.80 (0.01) | DAPA-CKD [34] |
| CKD G4 | 0.76 (0.01) | 0.85 (0.01) | 0.84 (0.01) | 0.79 (0.01) | DAPA-CKD [34] |
| CKD G5, pre-KRT | 0.73 (0.01) | 0.73 (0.01) | 0.83 (0.01) | 0.76 (0.01) | DAPA-CKD [34] |
| Dialysis | 0.68 (0.01) | 0.78 (0.01) | 0.79 (0.01) | 0.73 (0.01) | DAPA-CKD [34] |
| Transplant | 0.71 (0.07) | 0.71 (0.07) | 0.77 (0.01) | 0.74 (0.07) | DAPA-CKD [34] |
| Event-related disutility modifier | |||||
| HHF | –0.09 (0.04) | –0.08 (0.04) | –0.07 (0.03) | –0.06 (0.03) | DAPA-CKD [34] |
| Volume depletion | –0.05 (0.01) | –0.05 (0.01) | –0.05 (0.01) | –0.05 (0.01) | McEwan et al. [35] |
| Major hypoglycaemic events | –0.01 (0.00) | –0.01 (0.00) | –0.01 (0.00) | –0.01 (0.00) | Beaudet et al. [36]; Currie et al. [37] |
| Diabetic ketoacidosis | –0.01 (0.01) | –0.01 (0.01) | –0.01 (0.01) | –0.01 (0.01) | Peasgood et al. [38] |
| Fracture | –0.09 (0.03) | –0.05 (0.03) | –0.07 (0.03) | –0.05 (0.02) | DAPA-CKD [34] |
| Amputation | –0.26 (0.05) | –0.32 (0.05) | –0.26 (0.05) | –0.18 (0.04) | DAPA-CKD [34] |