Table 5.

Correlation coefficients between the level of depressive symptoms (measured by the general health questionnaire and four-dimensional symptom questionnaire) and both age and duration of treatment, divided by side effects of treatment with tyrosine kinase inhibitors

Side effects	Depressive symptoms	Age	Treatment duration
Fluid retention/oedema	GHQ	0.33*	0.61
	DSQ	0.95	–0.11
Frequent infections	GHQ	0.21	0.06
	DSQ	–0.04	–0.15
Fatigue	GHQ	0.30*	0.10
	DSQ	–0.05	–0.01
Bruising	GHQ	0.18	0.37
	DSQ	0.06	0.36
Diarrhoea	GHQ	0.47*	0.02
	DSQ	0.13	–0.13
Loss of appetite	GHQ	0.07	–0.03
	DSQ	–0.06	–0.18
Pleural effusions	GHQ	0.77	–0.70
	DSQ	–	–
Diabetes	GHQ	0.58	0.77
	DSQ	0.45	–0.70
Lipid disorders	GHQ	0.76*	0.37
	DSQ	–0.51	0.24
Bone and joint pain	GHQ	0.29*	0.07
	DSQ	0.15	–0.10
Nausea, indigestion	GHQ	0.18	–0.17
	DSQ	–0.01	0.11
Abdominal pain	GHQ	0.44	–0.09
	DSQ	0.16	–0.16
Cramps. muscle pain	GHQ	0.28*	0.04
	DSQ	0.10	–0.09
Skin rash, itching	GHQ	0.51*	0.32
	DSQ	0.36	0.67**

DSQ – dimensional symptom questionnaire, GHQ – general health questionnaire

^**p < 0.01; * p < 0.05