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. 2023 Dec 14;16(1):40–63. doi: 10.1038/s44321-023-00004-y

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© The Author(s) 2023, corrected publication 2024

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(A) Experimental scheme of CS_16mg inoculated mild septic mouse model. (B) Kaplan–Meier survival plot for mice administered with PBS or rWARS1 (20 mg/kg) after CS_16mg inoculation, naive mice were administered with PBS (n = 10 per group). (C, D) WARS1 levels in PLF (C) and plasma (D) at 15 h after CS inoculation (n = 3–6 per group). (E, F) Levels of cytokine and chemokine in PLF (E) and plasma (F) at 15 h after CS inoculation (n = 3–6 per group). (G–J) Serum levels of AST (G), ALT (H), BUN (I), and blood bacterial CFU (J) at 15 h after CS inoculation (n = 3–6 per group). Data information: Data are presented as mean ± SEM (C–J). Statistical analysis is performed with log-rank test (B), and ANOVA with Bonferroni corrections (C–J). ns, not significant; *p < 0.05, **p < 0.01, ***p < 0.001. Source data are available online for this figure.