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. 2023 Dec 18;20(1):28–55. doi: 10.1038/s44320-023-00004-7

Figure EV2. Summary of the phenotypic dose–response characteristics of all cell lines and all drugs.

Figure EV2

(A) Viability curves of five selected PI3K inhibitors in A204 cells. Measurements were in technical triplicates and the error bars were shown in SD. (B) Distribution of calculated EC50 values for all cell lines and all drugs. Numbers in brackets after each cell line name indicate the number of drugs that show effects larger than AUC>0.9 and have relative effect sizes of >50%. The red dotted line marks an EC50 value of 100 nM. The central band represents the median, while the hinges denote the first and third quartiles with whiskers extending up to 1.5 times the IQR.