Wood 2001.
| Methods | Type of trial: quasi‐RCT Number analysed/randomly assigned: 30/30 Intention‐to‐treat analysis: calculated | |
| Participants | Subacute neck pain | |
| Interventions | INDEX TREATMENT
Manual manipulation (A): technique: high‐velocity low‐amplitude manual adjustment; frequency: 2 to 3 sessions/wk; route: cervical spine COMPARISON Manipulation with Activator II (B): technique: manipulation using Activator II adjusting Instrument, mechanical force, manually assisted; frequency: 2 to 3 sessions/wk; route: cervical spine CO‐INTERVENTION: no medication ≥ 1 month; no other treatment modalities, exercises or education prescribed Duration of treatment: 4 weeks, 8 sessions Duration of follow‐up: 4 weeks |
|
| Outcomes | PAIN INTENSITY (NRS, 0 to 100)
Baseline mean: A 48.0, B 52.5
End of study mean: A 18.7, B 23.5
Absolute benefit: A 29.3, B 29.0
Reported results: not significant
SMD (A vs B): ‐0.29 (95% CI ‐1.01 to 0.43) FUNCTION (NDI, 0 to 50) Baseline mean: A 26.8, B 31.8 End of study mean: A 11.0, B 13.5 Absolute benefit: A 15.8, B 18.3 Reported results: not significant SMD (A vs B): ‐0.23 (95% CI ‐0.95 to 0.48) PATIENT SATISFACTION: NR GPE: NR QoL: NR SIDE EFFECTS: NR COST OF CARE: NR |
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| Notes | ||
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Low risk | Page 261, right column, paragraph 1 |
| Allocation concealment (selection bias) | Unclear risk | Unsure whether opaque and sealed envelopes were used |
| Blinding of Participants (performance bias) | High risk | Not possible owing to design |
| Blinding of Personal (performance bias) | High risk | Not possible owing to design |
| Blinding of the Outcome assessor (detection bias) | High risk | Not possible owing to design |
| Incomplete outcome data (attrition bias) | Unclear risk | Not described |
| Randomized Participants analysed were allocated (attrition bias) | Unclear risk | Not described |
| Selective outcome (reporting bias) | Unclear risk | No reported protocol |
| Similar groups at baseline? | Low risk | Table 5 |
| co‐interventions avoided or similar? | Unclear risk | Not described in Results section |
| Compliance acceptable? | Unclear risk | Not described |
| Similar timing of outcome assessment? | Low risk | Baseline, 4 weeks, 8 weeks |