Table 4:
Multivariable analysis of potential predictors of infant TST positivity at 44 weeks (n=727)
| TST result* |
Multivariable model |
|||
|---|---|---|---|---|
| Positive (n=55) | Negative (n=672) | Adjusted OR (95% CI) | p value | |
| Maternal study group | ||||
| Immediate isoniazid | 29 (53%) | 329 (49%) | 1·26 (0·70–2·30) | 0·44 |
| Deferred isoniazid | 26 (47%) | 343 (51%) | 1 (ref) | .. |
| Maternal CD4 count at entry, cells per mm3 | 610·5 (276·5) | 511·5 (235·1) | 1·11 (0·99–1·25) | 0·08 |
| Maternal TST positive at delivery (up to 6 weeks postpartum)† | 17 (31%) | 80 (11·9%) | 3·28 (1·70–6·33) | 0·0004 |
| Infant BCG scar present† | 51 (93%) | 535 (80%) | 4·97 (1·50–16·43) | 0·009 |
| Exclusive breastfeeding for any duration | 53 (96%) | 528 (79%) | 6·63 (1·57–27·92) | 0·010 |
Data are n (%) or mean (SD). OR indicates likelihood of TST positivity. BCG=Bacille Calmette-Guérin. TST=tuberculin skin test. OR=odds ratio.
TST positivity was defined as induration diameter ≥5 mm for infants with HIV and ≥10 mm for infants without HIV.
Only includes mother–infant pairs for whom data were available.