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. 2005 Apr 25;102(18):6338–6343. doi: 10.1073/pnas.0408563102

Fig. 2.

Fig. 2.

C. parvum recruits cholangiocyte SGLT1 to the attachment site and induces a localized glucose uptake in 603B cells. (A and B) Representative confocal micrographs showing accumulation of SGLT1 at the attachment site. (C) A representative real-time confocal micrograph showing an increased uptake of 2-NBDG at the attachment site (arrowheads). (D) No increase of 2-NBDG fluorescence at the attachment site was observed in the presence of phlorizin (arrowhead). (E) No increase of fluorescence for the control probe, 2-NBD, was found at the attachment site (arrowhead). (C-E Insets) The phase images of the same fields showing the parasite (arrowheads) in C-E. (F) Quantitative analysis of 2-NBD and 2-NBDG uptake at the attachment site. *, P < 0.05, ANOVA, C. parvum vs. control (fluorescence at the nearby region); *, P < 0.05 vs. C. parvum. (Scale bars: 5 μm.)