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C. parvum attachment to host-cell membrane activates c-Src/PI-3K pathways to induce actin remodeling at the parasite-attachment site. C. parvum also recruits host-cell SGLT1 and AQP1 to the attachment site and generates a localized water influx. This localized water influx facilitates membrane protrusion and thus benefits C. parvum cellular invasion.
