Table 1. The Myc-Mad-Max motifs, showing positional homology.
Amino acid number in basic and helix-1 sequence components | ||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Motif | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 |
Network | KNRS | KR | AKRST | HNQST | H | N | X | ALM | E | KRQ | HKNQR | R | R | X | X | ILMV | KR | X | X | FLY | X | X | L | HKR | DEGQT | X | ILMV | P |
Myc | KR | KR | KR | X | H | N | X | LM | E | R | X | R | R | X | DE | LM | KR | X | X | F | X | X | L | KR | DE | X | X | P |
Max | KR | KR | A | X | H | N | X | L | E | R | X | R | R | X | H | I | K | X | X | F | X | X | L | KR | DE | X | X | P |
Mad | X | R | EST | X | H | N? | EK | LM | E | K | X | R | R | A | X | L | RK | EL | CY | L | X | X | L | KR | X | X | X | P |
The Network motif includes Myc, Mad, Max, and other network proteins.